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    The International Society for Aerosols in Medicine

    IAC2018 Conference & Special Symposium: Aerosols in Medicine

    IAC2018 Conference & Special Symposium: Aerosols in Medicine

    26-Jun-2018


    Special Symposium: Aerosols in Medicine
    Monday, September 3rd

    Organizers: Andrew Martin (Univ. Alberta), Otmar Schmid (Helmholtz Zentrum Munchen), Philip Kuehl (Lovelace Biomedical)

    The symposium will bring together scientists and engineers working to apply aerosol physics and chemistry to medical applications, in particular to inhalation drug delivery. Recent advances in medical aerosol delivery technologies will be presented, as well as methods to evaluate and predict aerosol deposition and subsequent disposition. Topics will include in vitro and in silico techniques used to predict the delivered dose of aerosols to various regions of the respiratory tract, and new and emerging aerosol technologies for drug delivery and diagnostics.

    The symposium will be held over a single conference day, with morning and afternoon sessions that will include presentations from invited speakers and presentations selected from submitted abstracts. A poster session will be scheduled the same day, for additional submitted abstracts to be presented.

    Oral Presentations

    1MD AEROSOLS IN MEDICINE I - 260

    1MD.1
    9:45am
    Verifying the Hygroscopic Particle Growth Model during the Time Relevant to Lung Inspiration.
     PATRICK O'SHAUGHNESSY, Ralph Altmaier, Ross Walenga, Ching-Long Lin, University of Iowa
    1MD.2
    10:00am
    Regional Lung Deposition of Nebulized Hypertonic Saline for Trans-Nasal vs. Oral Inhalation in Healthy, Non-Smoking Adults.
     WILLIAM BENNETT, Kirby Zeman, Landon Holbrook, Katie Howe, Jihong Wu, David Busick, Richard Boucher, Scott Donaldson, University of North Carolina at Chapel Hill
    1MD.3
    10:15am
    Improved Prediction Of Intersubject Variability In Extrathoracic Aerosol Deposition.
     Conor A. Ruzycki, Michael Yang, Scott Tavernini, C. Paul Moore, Michelle L. Noga, Andrew R. Martin, Hak-Kim Chan, WARREN H. FINLAY,University of Alberta
    1MD.4
    10:30am
    Phenotyping of Chronic Obstructive Disease, COPD, from Deposition Fractions of Inhaled Nanoparticles.
     JAKOB LÖNDAHL, Jonas Jakobsson, H Laura Aaltonen, Eeva Piitulainen, Per Wollmer, Lund University, Sweeden
    1MD.5
    10:45am
    Validating CFD Predictions of Small Particle Aerosol Deposition in a Infant Nasal Airway Model.
     KARL BASS, Susan Boc, Michael Hindle, Worth Longest,Virginia Commonwealth University
    1MD.6
    11:00am
    Intranasal and Tracheal Deposition of Dry Particles in 3D Physical Models of Rhesus Macaques.
     JANA KESAVAN, Valerie J. Alstadt, Jerold Bottiger, Beth Laube, US ARMY ECBC
    1MD.7
    11:15am
    In Vitro Determination of Combivent and Spiriva Respimat Dose Delivery in Simulated Spontaneously Breathing Tracheostomy Patients.
     RYM MEHRI, Abubakar Alatrash, Edgar A. Matida, Fiorenza Frank, Carleton University, Ottawa, ON, Canada
    1MD.8
    11:30am
    Human Nasal Olfactory Deposition of Inhaled Nanoparticles.
     LIN TIAN, Yidan Shang, Jingliang Dong, Kiao Inthavong, Jiyuan Tu, RMIT University
     

    3MD AEROSOLS IN MEDICINE II - 260

    3MD.1
    3:45pm
    Improving Single Particle Aerosol Mass Spectrometry (SPAMS) Inhalation Analytics Performance through Rapid Particle Tracking and Sizing.
     MARTIN JETZER, Bradley Morrical, David Fergenson, Georgios Imanidis, Novartis Pharma AG
    3MD.2
    4:00pm
    Directly Measuring the Rapid Evaporation/Growth of Metered Dose Inhaler/Dry Powder Inhaler/Nebulizer Formulations.
     ALLEN E. HADDRELL, David Lewis, Tanya Church, Jonathan P. Reid, University of Bristol
    3MD.3
    4:15pm
    Biokinetics of Aerosolized Liposomal Ciclosporin a in Human Lung Cells in Vitro Using an Air-Liquid Cell Exposure System (Alice).
     OTMAR SCHMID, Corinne Jud, Yuki Umehara, Dominik Mueller, Albert Bucholski, Friedrich Gruber, Oliver Denk, Roman Egle, Alke Petri-Fink, Barbara Rothen-Rutishauser, Helmholtz Zentrum Munchen, Comprehensive Pneumology Center
    3MD.4
    4:30pm
    Formulation Development and In Vivo Pharmacokinetics of Topotecan for Targeted Treatment of Lung Cancer.
     PHILIP KUEHL, Michael Burke, Ramesh Chand, Devon Dubose, June Liu, Mathewos Tessema, Lovelace Biomedical, 2425 Ridgecrest Dr. SE, Albuquerque, NM
    3MD.5
    4:45pm
    Electrospray Functionalization of Titanium Dioxide Nanoparticles with Transferrin for Photodynamic Cancer Therapy.
     NATHAN REED, Ramesh Raliya, Rui Tang, Samuel Achilefu, Pratim Biswas, Washington University in St. Louis
    3MD.6
    5:00pm
    Synthesis of Large-Pore Submicron Mesoporous Silica using Salt-Assisted Spray Pyrolysis Method for Controlled Release Drug Delivery.
     Masoom Shaban, Jalal Poostforooshan, Sarah Reiser, Michael Türk, ALFRED P. WEBER, TU Clausthal

    Poster Session

    4MD AEROSOLS IN MEDICINE III

     

    4MD.1
    6:15pm
    Hyperthermic Intracavitary Nanoaerosol Therapy (HINAT) - a Promising Approach to Treat Peritonealcarcinomatosis. Daniel Göhler, Stephan Große, LARS HILLEMANN, Alexander Bellendorf, Thomas A. Falkenstein, Mehdi Ouaissi, Jürgen Zieren, Michael Stintz, Urs Giger-Pabst, Technische Universität Dresden
    4MD.2
    6:15pm
    Analysis of Xenon Mass Transfer from Human Upper Airway to Systemic Regions using a Hybrid CFD-PBPK Model. AHMADREZA HAGHNEGAHDAR, Jianan Zhao, Max Kozak, Patrick Williamson, Yu Feng, Oklahoma State University, Stillwater, OK, USA
    4MD.3
    6:15pm
    Aerosol Based Nanoscale Material Synthesis, Surface Engineering and Delivery to the Brain. RAMESH RALIYA, Nathan Reed, Debajit Saha, Dezhuang Ye, Tandeep Chadha, Hong Chen, Barani Raman, Pratim Biswas,Washington University in St. Louis
    4MD.4
    6:15pm
    Pores of Kohn: Forgotten Alveolar Structures and Potential Aerosol Generators? MICHAEL OLDHAM, Owen Moss, Altria Client Services LLC
    4MD.5
    6:15pm
    Characterization of Airspace Dimension Assessment with Nanoparticles (AiDA) on a Large Population and Relation to Anthropometry and Lung Function Parameters. JONAS JAKOBSSON, H Laura Aaltonen, Hanna Nicklasson, Sandra Diaz, Per Wollmer, Jakob Löndahl, Lund University
    4MD.6
    6:15pm
    Predicting Local and Systemic Distributions of Inhaled Budesonide Powders using In Vitro Experiments Combined with Numerical Modeling. CONOR A. RUZYCKI, Brynn Murphy, Hafeez Nathoo, Warren H. Finlay, Andrew R. Martin,University of Alberta
    4MD.7
    6:15pm
    Protein Aggregation Kinetics by Electrospray Differential Mobility Analysis.KALEB DUELGE, Vince Hackley, Michael Zachariah, University of Maryland, College Park
    4MD.8
    6:15pm
    Characterization of the Aerosol Flow, Sampling and Deposition in a Nose Only Exposure Chamber. FRANCESCO LUCCI, Wei Teck Tan, Subash Krishnan, Julia Hoeng, Patrick Vanscheeuwijck, Rudolph Jaeger, Arkadiusz Kuczaj, Philip Morris International R&D
    4MD.9
    6:15pm
    Method for the Production of "Universal" Inhalation Powders for Dry Powder Inhalers. Janne Raula, DAVID BROWN, Esko Kauppinen, Teicos Pharma
    4MD.10
    6:15pm
    Investigation of Single Particle Frictional Electrification with Polymer Plate.JIAWEI HU, Cai Liang, Lunbo Duan, Xiaoping Chen, Daoyin Liu, Changsui Zhao, School of Energy and Environment, Southeast University
    4MD.11
    6:15pm
    Patient Specific Deposition Enhancement of Nasal Sprays in Ct-Derived Human Nasal Replicas. Landon Holbrook, ALYSSA BURKE, Saikat Basu, Elizabeth Monaghan, Julia Kimbell, William Bennett, University of North Carolina at Chapel Hill